Case Report

Secondary chondrosarcoma: Malignant transformation of pre-existing hereditary and non-hereditary cartilaginous lesions

Susanna C.S. Vlok, Georg W.W. Wagener, Dan Zaharie
South African Journal of Radiology | Vol 18, No 2 | a703 | DOI: https://doi.org/10.4102/sajr.v18i2.703 | © 2014 Susanna C.S. Vlok, Georg W.W. Wagener, Dan Zaharie | This work is licensed under CC Attribution 4.0
Submitted: 28 July 2014 | Published: 15 December 2014

About the author(s)

Susanna C.S. Vlok, Division of Radiodiagnosis, Stellenbosch University and Tygerberg Hospital, South Africa
Georg W.W. Wagener, Division of Radiodiagnosis, Stellenbosch University and Tygerberg Hospital, South Africa
Dan Zaharie, Department of Anatomical Pathology, Stellenbosch University and Tygerberg Hospital, South Africa

Abstract

Secondary chondrosarcoma is a malignant hyaline cartilage tumour originating from a cartilaginous precursor, either osteochondroma or enchondroma. We contrast two different cases of biopsy-proven secondary chondrosarcomas resulting from benign, pre-existing cartilaginous lesions – our aim is to contrast and compare these two benign conditions consisting of multiple cartilaginous lesions – one hereditary and the other non-hereditary – and emphasise their potential for malignant transformation.

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