Clinical Perspective

The sandwich sign

Nasreen Mahomed, Halvani Moodley
South African Journal of Radiology | Vol 16, No 3 | a295 | DOI: https://doi.org/10.4102/sajr.v16i3.295 | © 2012 Nasreen Mahomed, Halvani Moodley | This work is licensed under CC Attribution 4.0
Submitted: 24 February 2012 | Published: 10 September 2012

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Nasreen Mahomed, university of witwatersrand, South Africa
Halvani Moodley, university of witwatersrand, South Africa


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Abstract

The sandwich sign refers to the sandwiching of mesenteric vessels and fat by enlarged mesenteric nodes on cross-sectional imaging, commonly occurring in lymphoma, but not specific to lymphoma. The sign is radiologically indistinguishable from post-transplant lymphoproliferative disorders. The radiological significance of the sandwich sign is in suggesting the diagnosis of lymphoma so that appropriate treatment may be initiated early as the tumour has a rapid growth pattern.

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