Case Report
Suprasellar pilocytic astrocytoma with leptomeningeal dissemination
Submitted: 13 February 2024 | Published: 27 May 2024
About the author(s)
Siti S. Mohamad Zaini, Department of Radiology, Hospital Kuala Lumpur, Kuala Lumpur, MalaysiaHilwati Hashim, Department of Radiology, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Malaysia
Emy S. Rosani, Department of Radiology, Hospital Sungai Buloh, Sungai Buloh, Malaysia
Nor S. Bakar, Department of Pathology, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Malaysia
Suryati Mohd Yusuf, Department of Pathology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
Abstract
Leptomeningeal dissemination is a rare manifestation of pilocytic astrocytoma. It may occur with higher-grade tumours like medulloblastoma, ependymoma and high-grade glioma, but is extremely rare with low-grade glioma. There has been a growing number of reported cases documenting leptomeningeal dissemination of pilocytic astrocytoma in the medical literature.
Contribution: Description of a World Health Organization (WHO) Grade I suprasellar pilocytic astrocytoma with leptomeningeal dissemination in the brain and spinal cord which showed progression of the leptomeningeal nodules without tumour upgrading on long-term follow-up.
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