Clinical Perspective

Face of the giant panda sign in Wilson disease

Sumit Chakraborty, Sumantro Mondal, Debanjali Sinha, Arijit Nag
South African Journal of Radiology | Vol 17, No 3 | a276 | DOI: https://doi.org/10.4102/sajr.v17i3.276 | © 2013 Sumit Chakraborty, Sumantro Mondal, Debanjali Sinha, Arijit Nag | This work is licensed under CC Attribution 4.0
Submitted: 24 February 2013 | Published: 01 August 2013

About the author(s)

Sumit Chakraborty, Department of Radiology and Imaging, Institute of Post Graduate Medical Education and Research, Kolkata, India
Sumantro Mondal, Department of General Medicine, Institute of Post Graduate Medical Education and Research, Kolkata, India
Debanjali Sinha, Department of General Medicine, Institute of Post Graduate Medical Education and Research, Kolkata, India, India
Arijit Nag, Department of General Medicine, Institute of Post Graduate Medical Education and Research, Kolkata, India, India


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Abstract

Wilson disease usually presents with neurologic or hepatic manifestations. Magnetic resonance imaging (MRI) of the brain is very informative in diagnosiing of this disease, especially in patients with neurological features. High T2 signal intensity in the corpus striatum is the most commonly encountered MRI finding. The 'face of the giant panda' sign is seen on axial T2-weighted MRI, and results from abnormal signal intensities in the midbrain. Though uncommon, the sign is considered as the pathognomonic MRI sign of Wilson disease.

Keywords

Face of panda sign; Wilson disease; MRI

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