Case Report

Correlative imaging and histopathology of a complicated sinonasal teratocarcinosarcoma

Tineke van Zyl, Leon Janse van Rensburg, Komeela Naidoo, Marc Merven, Johan F. Opperman
South African Journal of Radiology | Vol 27, No 1 | a2548 | DOI: https://doi.org/10.4102/sajr.v27i1.2548 | © 2023 Tineke van Zyl, Leon Janse van Rensburg, Komeela Naidoo, Marc Merven, Johan F. Opperman | This work is licensed under CC Attribution 4.0
Submitted: 31 August 2022 | Published: 30 January 2023

About the author(s)

Tineke van Zyl, Department of Maxillofacial Radiology, Faculty of Dentistry, University of the Western Cape, Cape Town, South Africa
Leon Janse van Rensburg, Department of Maxillofacial Radiology, Faculty of Dentistry, University of the Western Cape, Cape Town, South Africa; and, Department of Medical Imaging and Clinical Oncology, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa
Komeela Naidoo, Department of Radiation Oncology, Faculty of Medical Imaging and Clinical Oncology, Stellenbosch University, Cape Town, South Africa
Marc Merven, Department of Ear, Nose and Throat, Faculty of Medicine, Stellenbosch University, Cape Town, South Africa
Johan F. Opperman, Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, University of the Western Cape, Cape Town, South Africa; and, Department of Oral and Maxillofacial Pathology, National Health Laboratory Service, Cape Town, South Africa

Abstract

Sinonasal teratocarcinosarcoma (SNTCS) is a highly malignant and rare tumour characterised by a complex admixture of teratomatous and carcinosarcomatous components. In the head and neck area, it almost exclusively occurs in the sinonasal cavities; however, rare instances of nasopharyngeal and oral cavity involvement have been reported, with fewer than 100 cases reported in the literature.

Contribution: The contributed case involves the correlative CT, MRI and histopathology of a sinonasal teratocarcinosarcoma with intracranial involvement.


Keywords

Sinonasal teratocarcinosarcoma; histopathology; computerised tomography; magnetic resonance imaging; intracranial; diffusion-weighted imaging

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