Case Report

Radiology examination as a diagnostic aid in presentations with wide differential diagnoses: Case report of new Hodgkin’s lymphoma on a background of poorly controlled HIV

Rachel Hubbard, Jalpa Kotecha, Thomas Nash, Yu Jin Lee, Nasir Khan, Farhat Kazmi
South African Journal of Radiology | Vol 21, No 2 | a1239 | DOI: https://doi.org/10.4102/sajr.v21i2.1239 | © 2017 Rachel Hubbard, Jalpa Kotecha, Thomas Nash, Yu Jin Lee, Nasir Khan, Farhat Kazmi | This work is licensed under CC Attribution 4.0
Submitted: 07 June 2017 | Published: 14 November 2017

About the author(s)

Rachel Hubbard, Radiology Department, Chelsea and Westminster Hospital, United Kingdom
Jalpa Kotecha, HIV Department, Chelsea and Westminster Hospital, United Kingdom
Thomas Nash, Acute Assessment Unit, Chelsea and Westminster Hospital, United Kingdom
Yu Jin Lee, Radiology Department, Chelsea and Westminster Hospital, United Kingdom
Nasir Khan, Radiology Department, Chelsea and Westminster Hospital, United Kingdom
Farhat Kazmi, Radiology Department, Chelsea and Westminster Hospital, United Kingdom

Abstract

Hodgkin’s lymphoma and disseminated Mycobacterium avium complex (MAC) infection share similar clinical features; both may affect human immunodeficiency virus (HIV)-positive individuals. We discuss a patient with poorly controlled HIV-infection presenting with chest sepsis, dyspnoea and weight loss. Whilst the initial working diagnosis was that of MAC infection, pathology results had not met diagnostic criteria. Lymph node biopsy instead revealed classical Hodgkin’s lymphoma. We discuss the role of radiological examination in cases of diagnostic uncertainty.

Keywords

Human Immunodeficiency Virus; Hodgkin’s lymphoma; disseminated Mycobacterium avium complex; Radiology; Sepsis

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