Case Report

Unusual complication and successful high-dose chemotherapy treatment of advanced Burkitt’s lymphoma in an adult HIV-positive patient

Henrietta W.H. McGrath, Alexander Fitzhugh, Maria Javed, Neesha Rockwood, Farhat Kazmi
South African Journal of Radiology | Vol 21, No 2 | a1230 | DOI: https://doi.org/10.4102/sajr.v21i2.1230 | © 2017 Henrietta W.H. McGrath, Alexander Fitzhugh, Maria Javed, Neesha Rockwood, Farhat Kazmi | This work is licensed under CC Attribution 4.0
Submitted: 03 June 2017 | Published: 14 November 2017

About the author(s)

Henrietta W.H. McGrath, Department of Radiology, Chelsea and Westminster Hospital, United Kingdom
Alexander Fitzhugh, Department of Radiology, Chelsea and Westminster Hospital, United Kingdom
Maria Javed, Department of Radiology, Chelsea and Westminster Hospital, United Kingdom
Neesha Rockwood, Department of Infectious Diseases and HIV, Chelsea and Westminster Hospital, United Kingdom
Farhat Kazmi, Department of Radiology, Chelsea and Westminster Hospital, United Kingdom

Abstract

Adult Burkitt’s lymphoma emerged as an AIDS-defining condition in the 1980s. We describe a case of HIV-associated adult Burkitt’s lymphoma diagnosed and treated with high-dose chemotherapy in our institution, complicated by unusual bilateral renal vein tumour thrombi and tumour lysis syndrome. We believe this unique case highlights the need for early recognition of current and potential complications on staging computed tomography imaging, as well as successful use of a high-dose chemotherapy regimen.

Keywords

Burkitt's lymphoma; HI; renal vein thrombus

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