Original Research

Systolic function evaluated with cardiovascular magnetic resonance imaging in HIV-infected patients

Leonie Scholtz, André du Plessis, Savvas Andronikou, Anelia Swart, Anton Stoltz, Aneesah Khan, Aqeela Moosa
South African Journal of Radiology | Vol 20, No 2 | a1044 | DOI: https://doi.org/10.4102/sajr.v20i2.1044 | © 2016 Leonie Scholtz, André du Plessis, Savvas Andronikou, Anelia Swart, Anton Stoltz, Aneesah Khan, Aqeela Moosa | This work is licensed under CC Attribution 4.0
Submitted: 02 June 2016 | Published: 11 November 2016

About the author(s)

Leonie Scholtz, Department of Radiology, University of Pretoria, South Africa
André du Plessis, Scholtz and Partners Radiologists, Pretoria, South Africa
Savvas Andronikou, Department of Paediatric Radiology, Bristol Royal Hospital for Children, United Kingdom
Anelia Swart, Scholtz and Partners Radiologists, Pretoria,, South Africa
Anton Stoltz, Department of Internal Medicine, University of Pretoria, South Africa
Aneesah Khan, Department of Radiology, University of Pretoria, South Africa
Aqeela Moosa, Faculty of Health Sciences, University of Pretoria, South Africa


Background: Of all areas worldwide, sub-Saharan Africa is worst affected by the HIV and/or AIDS epidemic. Cardiovascular manifestations are very common and are a powerful contributor to mortality, but often go undetected. Cardiovascular magnetic resonance (CMR) is the most reliable method of assessing cardiac function and morphology and, with this in mind, we initiated a cross-sectional study comparing CMR-determined morphological and functional parameters in asymptomatic HIV-infected patients who were not yet on treatment and early in the disease, with HIV-uninfected control patients.

Objectives: To ascertain whether there were any morphological abnormalities or systolic functional impairments on CMR in untreated asymptomatic HIV-infected patients, compared with HIV-uninfected control individuals.

Methods: The CMR studies were performed using a 1.5-T whole-body clinical magnetic resonance 16-channel scanner (Achieva, Philips Medical Systems, Best, The Netherlands), using a cardiac five-element phased-array receiver coil (SENSE coil). Functional assessment was performed on 36 HIV-infected patients and the findings compared with 35 HIV-uninfected control patients who were matched for age and sex.

Results: There was no significant difference in systolic function between the HIV-uninfected and the HIV-infected patients. The left ventricular end diastolic mass (LVEDM) was slightly higher in the HIV-infected group, but this was statistically insignificant.

Conclusion: No significant differences were found regarding the CMR systolic functional analysis and morphological parameters between the HIV-infected and the healthy volunteers.


HIV CMR Functional analysis


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