Case Report
Anti-Ma2-antibody-associated encephalitis: An atypical paraneoplastic neurologic syndrome
Submitted: 15 January 2018 | Published: 17 May 2018
About the author(s)
Bogna Targonska, Department of Radiology, Renown Regional Medical Center, Reno, NV, United StatesJamie Frost, Helen DeVos Childrens Hospital, Advanced Radiology Services, Grand Rapids, MI, United States
Sanjay Prabhu, Department of Radiology, Boston Children’s Hospital, Boston, MA, United States
Abstract
Paraneoplastic syndromes are a heterogeneous group of conditions affecting cancer patients, where the signs and symptoms are not owing to the local effects of the tumour but instead owing to humoral or immunologic effects. We describe an unusual presentation of a paraneoplastic neurologic syndrome presenting with predominant involvement of the hypothalamus and deep grey nuclei secondary to an anterior mediastinal germinoma and associated with anti-Ma2 antibody.
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RadioGraphics vol: 39 issue: 4 first page: 1019 year: 2019
doi: 10.1148/rg.2019180050